My Alphaderma-CE Review

Alpha Derma CE ImageAlphaderma CE is made by Janson Beckett Cosmeceuticals and was first introduced in 2004 as their first peptide formulation. It is hailed by skin care industry experts as one of the premiere formulations for restoring skin to its most youthful appearance. Alphaderma CE has a fiercely, loyal customer base and remains the company’s flagship product.

Alphaderma CE contains the potent concentrations of clinically proven ingredients like Argireline, Alpha Lipoic Acid, Vitamin C Ester, DMAE, Elastin, Collagen, Soy, Aloe Vera, Glycerin, and essential trace minerals that are vital to healthy skin. But there are some ingredients that aren't effective and may not be good for your health. Keep reading to find out the truth.

AlphaDerma CE's Manufacturing Guidelines

It is manufactured under strict guidelines to assure that stringent quality controls are never compromised. Alphaderma CE is never tested on animals. This company quite obviously has a long established excellent reputation.

Ingredient lists are readily available at the website which is very professional. Alphaderma CE is also billed as a stretch mark treatment.

Alphaderma CE costs $129.95 for 4 oz., which works out to $1.22 per day. Ground shipping within the continental US is free for orders over $49. has an good refund policy: items returned within 30 days are eligible for a full refund. You must call or email to coordinate the return with an RMA number, the original invoice, and the unused portion of the product. offers an autoship program which can save you 10% on future orders.

Product Claims:

  • Quickly Removes Appearance of Fine Lines & Wrinkles
  • Repairs & Prevents Damaged Skin
  • Immediately Tightens & Firms Aged Skin
  • Achieve Visible Results after Just One Treatment

Cross Examination:

Ingredient list: Demineralized Spring Water, Acetyl Hexapeptide 3, Octyl Methoxycinnamate, Glycerine, Olive Oil, Oxybenzone, Soybean Oil, Stearic Acid, Hydrolyzed Soy Protein, Soluble Collagen, Hydrolyzed Elastin, Alpha Lipoic Acid, Ascorbyl Palmitate, DMAE Bitartrate, Aloe Vera Extract, Glyceryl Stearate, Allantoin, Citric Acid, Microcrystalline Cellulose, Cetyl Alcohol, Simethicone, Methylparaben, Propylparaben, Cetearyl Alcohol, Ceteareth-20, Tea Carbomer 940.

Alphaderma CE has several quality ingredients that make it a good product. For example, it contains argireline™, which is touted as the alternative to Botox™, the stabilized form of vitamin C (ascorbyl palmitate), and DMAE, which has been clinically shown to reduce the appearance of fine lines and wrinkles.

Alpha lipoic acid is included in the formulation, and while it is not the most powerful anti-oxidant out there, it is a good anti-oxidant. It does have clinically proven abilities to reduce skin roughness and the appearance of wrinkles.

Alphaderma CE also contains oxybenzone, which is a sunscreen. All these ingredients are good things, but for $129? If you have read my other reviews, these ingredients, while fairly good anti-aging substances, are commonly found in creams that are lesser priced.

The Lowdown on Collagen

It is my hope that my readers are now empowered consumers, and should have red flags raised at the claims of this company that their collagen and elastin penetrate the cell membrane and do anything at the cellular level. First of all, soluble or not, collagen molecules are too big to penetrate squamous skin cells. Collagen just sits on the surface of the skin, hydrating well, but just waiting to be washed off at your next cleansing. Hydrolyzed elastin is chopped into tiny pieces, and even though it may be small enough to penetrate the cellular barrier, it is too small to be incorporated into cell structure. Most likely, it is just scavenged by the cells in your body that fight viruses, bacteria, and other foreign invaders. So the collagen and elastin are bogus ingredients that really do nothing.

Speaking of foreign, what the makers of Alphaderma CE don’t tell you is that their collagen and elastin sources are most likely chicken and cow, and are not regulated by the FDA. So I have to ask you: even if chicken and/or cow proteins could merge into your own skin cell’s structure, the question is, would you really want them to?

Alphaderma CE does come in a container that protects it from light and oxygen.

The Bottom Line:

With Argireline™, DMAE, a stable ester of vitamin C, and alpha lipoic acid, I think that this product is not half bad, but the addition of collagen and elastin throw this to the undesireable side. And there are some things that are missing for the $129 price tag.

For example, even though they say you will have instant results, all the ingredients they listed are more gradual and cumulative in their effect, and take time to have results. If they would have added light reflecting particles to make wrinkles appear smaller, you would see immediate results while waiting for the full effects of Argireline™ and DMAE. There are other products like LifeCell that have this included, so you see wrinkles diminish before your eyes.

The emphasis on collagen and elastin puts me off: the product is good without the inclusion of these ingredients and it actually makes Alphaderma CE less attractive to me. Why use ingredients that have questionable safety and efficacy? Prions (the basis of mad cow disease) exist in proteins such as collagen and elastin, and science is just starting to understand this elusive disease. While the risk is small, why chance it at all?

However, if you do choose to try it out, there is the 30 day return period, so you have time to see if this product is right for you.